welcome
We study the genetic basis of complex traits and common diseases in humans. Our group is located in the Harvard Medical School-Partners Healthcare Center for Genetics and Genomics and the Division of Genetics in the Department of Medicine of the Brigham and Women's Hospital and Harvard Medical School. We are also in the Program in Medical and Population Genetics at the Broad Institute of Harvard and MIT.
A central goal of our lab is to develop computational tools and statistical approaches to analyze patterns of genetic variation in human populations, and to apply these methods to identify genetic determinants of disease susceptibility, disease progression, and drug response.
We pursue these activities primarily in the context of HIV/AIDS, but we also work on autoimmune disease, and cerebrovascular and cardiovascular traits, involving many collaborators in Boston and elsewhere.
opportunities
Opportunities exist for talented and motivated individuals (students, postdocs, fellows, programmers, (bio)statisticians) to join our research activities. Please check out the Projects page and send email enquiries to Paul de Bakker.
news
Scaling up for a deeper look at diabetes [4 April 2008]
Gates funds study of HIV controllers [21 March 2008]
New chapter for HapMap [17 October 2007]
Risk genes for multiple sclerosis uncovered [29 July 2007]
New genomic tool for diabetes [12 February 2007]
With HapMap, one size fits many [23 October 2006]
Researchers map genetic variability in key immune region [25 September 2006]
Gene's forecast of diabetes not carved in stone [19 July 2006]
Sizing up "SNP chips" [31 May 2006]
Genetic Road Map Drawn for Tracing Route To Common Diseases [11 November 2005]
Haplotype map brings new insights into human disease, evolution [26 October 2005]
First edition of HapMap released, a "catalog" of human genetic variation [26 October 2005]