welcome
We study the genetic basis of complex traits and common diseases in humans. Our group is in the Division of Genetics in the Department of Medicine of the Brigham and Women's Hospital and Harvard Medical School. We are also affiliated with the Program in Medical and Population Genetics at the Broad Institute of Harvard and MIT.
A central goal of our lab is to develop computational tools and statistical approaches to analyze patterns of genetic variation in human populations, and to apply these methods to identify genetic determinants of disease susceptibility, disease progression, and drug response.
We pursue these activities in the context of immune-related disorders including HIV/AIDS and autoimmune disease, as well as cerebrovascular and cardiovascular traits, involving many collaborators in Boston and elsewhere.
opportunities
Opportunities exist for talented and motivated individuals (students, postdocs, fellows, programmers, (bio)statisticians) to join our research activities. Please send email enquiries to Paul de Bakker. Also check out the opportunities page of the Division of Genetics.
news
Gene Study First Step to Predicting Cardiac Drug Toxicity [HMS FOCUS 3 April 2009]
Common gene variants influence risk factor for sudden cardiac death [MGH 23 March 2009]
The rare few (a story about HIV controllers) [MGH PROTO Jan/Feb 2009]
Large study helps unearth cholesterol's genetic roots [Broad 8 December 2008]
A unique collaboration between Cambridge and Silicon Valley [Broad 7 September 2008]
Charting the genome's landscape [Broad 7 September 2008]
Scaling up for a deeper look at diabetes [Broad 4 April 2008]
Gates funds study of HIV controllers [HMS FOCUS 21 March 2008]
New chapter for HapMap [Broad 17 October 2007]
Risk genes for multiple sclerosis uncovered [Broad 29 July 2007]
Genomic tour de force for diabetes [Broad 27 April 2007]
New genomic tool for diabetes [Broad 12 February 2007]
With HapMap, one size fits many [Broad 23 October 2006]
Researchers map genetic variability in key immune region [Broad 25 September 2006]
Gene's forecast of diabetes not carved in stone [Broad 19 July 2006]
Sizing up "SNP chips" [Broad 31 May 2006]
Genetic Road Map Drawn for Tracing Route To Common Diseases [HMS FOCUS 11 November 2005]
Framework for a fully powered risk engine [Nature November 2005]
Haplotype map brings new insights into human disease, evolution [Broad 26 October 2005]
First edition of HapMap released, a "catalog" of human genetic variation [Broad 26 October 2005]
